Lactose Malabsorption

To determine the prevalence of lactose malabsorption in young Lithuanian atopic dermatitis children; to evaluate the relationship between lactose malabsorption and the duration of exclusive breastfeeding, and the relationship between lactose malabsorption and cow's milk intolerance in parents and grandparents. Methods: 144 children with atopic dermatitis aged 1.5-24 mo (study group) and 32 children without symptoms of allergic diseases (control group) were investigated. Lactose and glucose-galactose absorption tests based on serial blood glucose determination, culture of stool, latex agglutination test for rotavirus and microscopic examination of stool for parasites were performed. Lactose malabsorption was determined in 59 (40.9%) and glucose-galactose malabsorption in 17 (11.8%) children with atopic dermatitis. The risk of developing lactose malabsorption was higher in children fed exclusively on breast milk up to 1 month of age than in children fed exclusively on breast milk for 4 to 6 months (OR: 2.62). Lactose malabsorption was significantly more frequent in patients whose mothers did not tolerate cow's milk (66.7%) than in patients whose mothers were tolerant to it (41.1%). Conclusion: Lactose malabsorption was determined in 40.9% of Lithuanian atopic dermatitis children aged under 2 years. Lactose malabsorption appeared to be associated with brief duration of exclusive breastfeeding (less than 1 month) and mothers' milk intolerance.
Rudzeviciene O et al. “Lactose malabsorption in young Lithuanian children with atopic dermatitis.” Acta Paediatrica. Apr 2004; 93 (4) : 482-486.

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